Needlestick Distal Nerve Injury in Rats Models Symptoms of Complex Regional Pain Syndrome

Needlestick distal nerve injury in rats models symptoms of complex regional pain syndrome.

BACKGROUND Complex Regional Pain Syndrome (CRPS)-I consists of chronic limb pain and dysautonomia triggered by traumas that sometime seem too trivial to be causative. Several pathological studies have identified minor distal nerve injuries (DNIs) in CRPS-I patients, but retrospective studies cannot establish causality. Therefore, we, prospectively investigated whether DNIs are sufficient to cau...

Endoneurial pathology of the needlestick-nerve-injury model of Complex Regional Pain Syndrome, including rats with and without pain behaviors.

Current rodent models of neuropathic pain produce pain hypersensitivity in almost all lesioned animals and not all identified experimental effects are pain specific. 18G needlestick-nerve-injury (NNI) to one tibial nerve of outbred Sprague-Dawley rats models the phenotype of Complex Regional Pain Syndrome (CRPS), a post-traumatic neuropathic pain syndrome, leaving roughly half of NNI rats with ...

continuous peripheral nerve catheters in pediatric complex regional pain syndrome

rethinking the psychogenic model of complex regional pain syndrome: somatoform disorders and complex regional pain syndrome

abstract explaining the etiology of complex regional pain syndrome (crps) from the psychogenic model is exceedingly unsophisticated, because neurocognitive deficits, neuroanatomical abnormalities, and distortions in cognitive mapping are features of crps pathology. more importantly, many people who have developed crps have no history of mental illness. the psychogenic model offers comfort to ph...

Continuous Peripheral Nerve Catheters in Pediatric Complex Regional Pain Syndrome

Complex regional pain syndrome (CRPS) is outlined as a painful and disabling syndrome accompanied by physical changes within the affected extremity, together with allodynia, edema, and baldness, yet as sudomotor and dilatation dysfunction CRPS has been reported most often in adult population, but it has been reported in pe-diatric population as well. Although several modalities are tried for th...